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Top 25 Biotech Companies of 2024

Article originally published on GEN The biotechnology industry achieved many firsts this past year, from the first approved drug that can slow the rates of cognitive and functional decline in adults with Alzheimer’s disease, to the first CRISPR-based gene editing...

PEGylation Technology

PEGylation is the chemical linkage of polyethylene glycol polymer chains to various APIs, primarily to increase in vivo half-life and stability of the product. BioTechLogic has experience managing pre-qualification and optimization studies for PEGylation reactions. Our experience includes the development and validation of the following reaction parameters:

  • Molar ratio of PEG reagent to product
  • Time
  • Temperature
  • Mixing and static reactions
  • Reagent stability
  • In-process hold times